Finally, conjugation products that are easy to use, stable in solution, make better conjugates, and are applicable to almost any conjugation problem! SoluLink conjugation products are highly selective, stable in solution, and not susceptible to non-specific binding, making them superior to conventional methods.
Traceability The bis-aryl hydrazone bond formed with HyNic and 4FB absorbs at 354?nm with a molar extinction coefficient of 29,000.
Reproducibility Biomolecule modification can be quantified for greater batch-to-batch reproducibility.
Linker Stability Biomolecules modified with HyNic and 4FB have extended reaction stabilities.
Bond Stability Bis-aryl hydrazones are stable to temperatures up to 94°C and a wide pH range of pH 2–11.
Specific SoluLinK bioconjugation chemistry assures formation of heteroconjugates, with no formation of homoconjugates. Reactive moieties on modified biomolecules are inert and do not react with protein functional groups.
Aqueous Chemistry Reactions are carried out in aqueous buffered solutions with high efficiency.
Versatility Our chemistry has been engineered to conjugate and immobilize proteins, oligonucleotides, peptides, and carbohydrates.
Solid Phase Synthesis Linkers can be incorporated in both peptides and oligonucleotides during solid phase synthesis.