Description: HydraLinkTM conjugation chemistry is based on the reaction of a HyNic functional group with a 4FB moiety to form a stable bis-aryl hydrazone bond. The bond created is a Schiff base that is both stable and UV-traceable. This unique covalent bond is created when hydrazinonicotinamide (HyNic), incorporated into one type of biomolecule reacts with a formylbenzamide moiety (4FB), incorporated into a second biomolecule. This type of hydrazone bond formed is the only known example of a stable Schiff base, which requires no additional steps (reduction) to stabilize the bond.
Catalog Number:
S-9002-1
Size:
Kit
Price:
$495.00
S-HyNic (SANH) 5 x 1.0 mg
Description:
S-HyNic (SANH) introduces traceable HyNic (6-hydrazinonicotinamide) moieties onto proteins or other amine containing biomolecules and surfaces. S-HyNic is an amine-reactive succinimidyl ester derivative of the acetone hydrazone of 6-hydrazinonicotinic acid. S-HyNic reacts with primary amines on a protein's (ε-amino group of lysine), amino-modified oligonucleotides or surface introducing HyNic moieties that form stable bis-arylhydrazone-based conjugates with other biomolecules possessing 4FB (4-formylbenzamide) moieties.
Catalog Number:
S-1002-105
Size:
5 x 1.0 mg
Price:
$150.00
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S-HyNic (SANH) 10 mg
Description:
S-HyNic (SANH) introduces traceable HyNic (6-hydrazinonicotinamide) moieties onto proteins or other amine containing biomolecules and surfaces. S- HyNic is an amine-reactive succinimidyl ester derivative of the acetone hydrazone of 6-hydrazinonicotinic acid. S-HyNic reacts with primary amines on a proteins (ε-amino group of lysine), amino-modified oligonucleotides or surfaces introducing HyNic moieties that form stable bis-arylhydrazone-based conjugates with other biomolecules possessing 4FB (4-formylbenzamide) moieties.
Catalog Number:
S-1002-010
Size:
10 mg
Price:
$225.00
Technetium Conjugation SHNH Kit
Description:
SHNH, used for linking technetium-99m, readily reacts with primary amines on a protein (Epsilon-amino grop of lysine) via an NHS-ester. SHNH introduces tracebalbe HyNic (hydrazinonicotinamide) groups onto proteins or other amine-containing biomolecules. Technetium labeling of biomolecules has been widely used. Over 200 references can be found by searching PubMed; keyword HyNic.
Catalog Number:
S-9001-2
Size:
Kit
Price:
$425.00
SHTH Conjugation Kit
Description:
The SHTH Bioconjugation Kit provides a powerful yet simple technology for labeling peptides, proteins, carbohydrates, and nucleic acids. The kit provides the heterobifunctional linkers S-4FB and SHTH along with reagents for quantifying fluorophores, biotin and other tags with a variety of proteins.
Catalog Number:
S-9003
Size:
Kit
Price:
$425.00
Technetium Conjugation Reagent SHNH 10 mg
Description:
SHNH (Succinimidyl 6-hydraziniumnicotinate hydrochloride) is used to incorporate HyNic (hydrazinonicotinamide) moieties on proteins, peptides and other amine containing molecules for technetium-99M labeling. Over 200 references describing the use of HyNic-modified biomolecules for technetium-99M labeling can be found by searching PubMed; keyword HyNic.
Catalog Number:
S-1001-010
Size:
10 mg
Price:
$250.00
Conjugation Reagent C6-S-HyNic (C6-SANH) 5 x 1.0 mg
Description:
C6-HyNic (SANH) has a six carbon chain incorporated onto S-Hynic, one of SoluLink's most popular conjugation reagents. Works especially well for protein conjugations. Why would you need a six carbon linker ? The extended linker is useful when steric blocking interferes with conjugations especially in the conjugation of two rpoteins. Heterobifunctional linker used for making all types of conjugates by introducing aromatic hydrazines into biomolecules that are UV-traceable meaning the resulting conjugate is quantifiable. Reactive groups are NHS-ester and protected aromatic hydrazine. Reactive towards amino groups and aromatic aldehydes.
Catalog Number:
S-1010-105
Size:
5 x 1.0 mg
Price:
$175.00
Conjugation Reagent C6-S-HyNic (C6-SANH) 10 mg
Description:
C6-HyNic(SANH) has a six carbon chain incorporated onto S-Hynic, SoluLink's most popular conjugation regeant, works especially well for protein conjugations. Why would you need a six carbon linker ? The extended linker is useful when steric blocking interferes with conjugations especially in the conjugation of two rpoteins. Heterobifunctional linker used for making all bioconjugates; introduces aromatic hydrazines into biomolecules, UV-traceable, Reactive groups are NHS-ester,protected aromatic hydrazine;Reactive towards;amino groups,aromatic aldehydes.
Catalog Number:
S-1010-010
Size:
10 mg
Price:
$250.00
SHTH Conjugation Kit
Description:
The SHTH reagent is used to convert promary amines on biomolecules and surfaces to 4-hydrazidobenzamide moiieties in a single step. Its advantages include reaction specificity, UV-traceability, and the unique control it brings to the entire conjugation process. SHTH readily reacts with primary amines on a protein (Epsilon-amino group of lysine) via an NHS-ester.
Catalog Number:
S-1003-010
Size:
10 mg
Price:
$225.00
Conjugation Reagent MHPH
Description:
MHPH is used to convert thiol moieties on biomolecules and surfaces to 2-hydrazinopyridine moieties in a single step. Its advantages include reaction specificity, UV-traceability, and the unique control it brings to the entire conjugation process. 2-hydrazinopyridine-modified proteins then react to form stable conjugates in the presence of other (aromatic) aldehyde-modified proteins or biomolecules.
